头颈部恶性黑色素瘤11例临床分析
【摘要】 目的 探讨头颈部恶性黑色素瘤的临床表现、临床分期、治疗和预后。方法 回顾分析我院收治的11例恶性黑色素瘤患者，6例行手术、放疗和化疗，5例行手术加免疫治疗。结果 完全缓解2例，部分缓解5例，无效为4例，随访3～5年，3年生存者为4例，5年生存者为0例。结论 恶性黑色素瘤患者预后差，生存期短，治疗以手术治疗为主，采用免疫治疗辅助手术效果更好。【关键词】 恶性黑色素瘤；免疫治疗；头颈
Clinical analysis of 11 cases m alignant melanoma in head and neck
ZHANG Ying-hua,SHENG Cai-hua,FAN Ben-chu.Department of Otolaryngology,the Second People’s Hospital of Xinyang.Henan,464000，China
【Abstract】 Objective To analyze and discuss the Clinial feature,Clinical stage,treatment and Prognosis of head and neck m alignant melanoma.Mothods The treatmemt mothods and Prognosis of 11 cases of m alignant melanoma from 1988-2003 were reviewed and analyzed.6 patients received surgery,radiotherapy and chmotherapy,5 patients recrived surgery and immunotherapy.Results 2 patients achieved complete remission,5 patients achieved partial remission.All patients had follow-up,ranging from 3~5 years,3 year survival case was zero. Conclusion M alignant melanoma had poor prognosis, the effect of combination of opetation and immunotherapy was better than the combination of operation, radiotherapy and chemotherapy. ......
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