龙葵碱抗肿瘤作用及机制(5)
[29]房昭，杨爱莲，高福云，等.龙葵碱诱导人宫颈癌细胞HeLa凋亡的体外实验研究[J].华西药学杂志，2010，25(3)：266268.
[30]郝敬全，刘璇，温少瑾，等.龙葵总碱对骨髓瘤细胞凋亡及NFκB表达的影响[J].湖南中医杂志，2013，29(9)：126129.
[31]Li X，Zhao Y，Wu WK，et al.Solamargine induces apoptosis associated with p53 transcriptiondependent and transcriptionindependent pathways in human osteosarcoma U2OS cells[J].Life Sci，2011，88(78)：314321.
[32]Sun L，Zhao Y，Li X，et al.A lysosomalmitochondrial death pathway is induced by solamargine in human K562 leukemia cells[J].Toxicol In Vitro，2010，24(6)：15041511.
, 百拇医药
[33]Li X，Zhao Y，Ji M，et al.Induction of actin disruption and downregulation of Pglycoprotein expression by solamargine in multidrugresistant K562/A02 cells.Chin Med J(Engl)[J].2011，124(13)：20382044.
[34]Wu CH，Liang CH，Shiu LY，et al.Solanum incanum extract(SRT100)induces human cutaneous squamous cell carcinoma apoptosis through modulating tumor necrosis factor receptor signaling pathway[J].J Dermatol Sci.2011，63(2)：8392.
[35]季宇彬，劉家源，高世勇.龙葵碱对乳腺癌MCF7细胞微管系统的影响[J].中草药，2012，43(1)：111114.
, 百拇医药
[36]Cui CZ，Wen XS，Cui M，et al.Synthesis of solasodine glycoside derivatives and evaluation of their cytotoxic effects on human cancer cells[J].Drug Discov Ther.2012，6(1)：917.
[37]Ding X，Zhu FS，Li M，et al.Induction of apoptosis in human hepatoma SMMC7721 cells by solamargine from Solanum nigrum L[J].J Ethnopharmacol，2012，139(2)：599604.
[38]章俊，施国伟.龙葵碱对前列腺癌细胞系PC3的体外抑制作用[J].中华男科学杂志，2011，17(3)：284287.
, 百拇医药
[39]Li S，Wang L，Hu Y，et al.Autophagy regulators as potential cancer therapeutic agents：a review[J].Curr Top Med Chem，2015，15(8)：720744.
[40]Hasanain M，Bhattacharjee A，Pandey P，et al.αSolanine induces ROSmediated autophagy through activation of endoplasmic reticulum stress and inhibition of Akt/mTOR pathway[J].Cell Death Dis，2015，6(8)：1860.
[41]Hu B，An HM，Wang SS，et al.Preventive and therapeutic effects of Chinese herbal compounds against hepatocellular carcinoma[J].Molecules，2016，21(2)：142.
, 百拇医药
[42]Shang Y，Cai X，Fan D.Roles of epithelialmesenchymal transition in cancer drug resistance[J].Curr Cancer Drug Targets，2013，13(9)：915929.
[43]Lai YJ，Tai CJ，Wang CW，et al.Anticancer activity of Solanum nigrum(AESN)through suppression of mitochondrial function and epithelialmesenchymal transition(EMT)in breast cancer cells[J].Molecules，2016，21(5)：553.
[44]Shen KH，Liao AC，Hung JH，et al.αSolanine inhibits invasion of human prostate cancer cell by suppressing epithelialmesenchymal transition and MMPs expression[J].Molecules，2014，19(8)：1189611914., 百拇医药(闫霞郑佳露胡兵)
[30]郝敬全，刘璇，温少瑾，等.龙葵总碱对骨髓瘤细胞凋亡及NFκB表达的影响[J].湖南中医杂志，2013，29(9)：126129.
[31]Li X，Zhao Y，Wu WK，et al.Solamargine induces apoptosis associated with p53 transcriptiondependent and transcriptionindependent pathways in human osteosarcoma U2OS cells[J].Life Sci，2011，88(78)：314321.
[32]Sun L，Zhao Y，Li X，et al.A lysosomalmitochondrial death pathway is induced by solamargine in human K562 leukemia cells[J].Toxicol In Vitro，2010，24(6)：15041511.
, 百拇医药
[33]Li X，Zhao Y，Ji M，et al.Induction of actin disruption and downregulation of Pglycoprotein expression by solamargine in multidrugresistant K562/A02 cells.Chin Med J(Engl)[J].2011，124(13)：20382044.
[34]Wu CH，Liang CH，Shiu LY，et al.Solanum incanum extract(SRT100)induces human cutaneous squamous cell carcinoma apoptosis through modulating tumor necrosis factor receptor signaling pathway[J].J Dermatol Sci.2011，63(2)：8392.
[35]季宇彬，劉家源，高世勇.龙葵碱对乳腺癌MCF7细胞微管系统的影响[J].中草药，2012，43(1)：111114.
, 百拇医药
[36]Cui CZ，Wen XS，Cui M，et al.Synthesis of solasodine glycoside derivatives and evaluation of their cytotoxic effects on human cancer cells[J].Drug Discov Ther.2012，6(1)：917.
[37]Ding X，Zhu FS，Li M，et al.Induction of apoptosis in human hepatoma SMMC7721 cells by solamargine from Solanum nigrum L[J].J Ethnopharmacol，2012，139(2)：599604.
[38]章俊，施国伟.龙葵碱对前列腺癌细胞系PC3的体外抑制作用[J].中华男科学杂志，2011，17(3)：284287.
, 百拇医药
[39]Li S，Wang L，Hu Y，et al.Autophagy regulators as potential cancer therapeutic agents：a review[J].Curr Top Med Chem，2015，15(8)：720744.
[40]Hasanain M，Bhattacharjee A，Pandey P，et al.αSolanine induces ROSmediated autophagy through activation of endoplasmic reticulum stress and inhibition of Akt/mTOR pathway[J].Cell Death Dis，2015，6(8)：1860.
[41]Hu B，An HM，Wang SS，et al.Preventive and therapeutic effects of Chinese herbal compounds against hepatocellular carcinoma[J].Molecules，2016，21(2)：142.
, 百拇医药
[42]Shang Y，Cai X，Fan D.Roles of epithelialmesenchymal transition in cancer drug resistance[J].Curr Cancer Drug Targets，2013，13(9)：915929.
[43]Lai YJ，Tai CJ，Wang CW，et al.Anticancer activity of Solanum nigrum(AESN)through suppression of mitochondrial function and epithelialmesenchymal transition(EMT)in breast cancer cells[J].Molecules，2016，21(5)：553.
[44]Shen KH，Liao AC，Hung JH，et al.αSolanine inhibits invasion of human prostate cancer cell by suppressing epithelialmesenchymal transition and MMPs expression[J].Molecules，2014，19(8)：1189611914., 百拇医药(闫霞郑佳露胡兵)